Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II; Complex I is essential in autophagy, Complex II is required for vacuolar protein sorting; required for overflow degradation of misfolded proteins when ERAD is saturated; C-terminus has novel globular fold essential for autophagy through the targeting of the PI3-kinase complex I to the pre-autophagosomal structure; ortholog of higher eukaryote gene Beclin 1; human BECN1 can complement yeast null mutant [Source:SGD;Acc:S000006041]

APG6, ATG6, VPT30

Chromosome XVI: 322,071-323,744 forward strand.

This transcript has 1 exon, is annotated with 17 domains and features, is associated with 48 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YPL120W Show transcript tableHide transcript table