Ubiquitin-protein ligase (E3); controls septin dynamics and spindle position checkpoint (SPOC) with ligase Dma1p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ortholog of human RNF8, similar to human Chfr; contains FHA and RING finger domains; DMA2 has a paralog, DMA1, that arose from the whole genome duplication [Source:SGD;Acc:S000005060]
CHF2
Chromosome XIV: 408,341-409,909 forward strand.
This transcript has 1 exon, is annotated with 18 domains and features, is associated with 30 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YNL116W Show transcript tableHide transcript table
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YNL116W_mRNA | DMA2 | 1569 | 522aa | YNL116W | Protein coding | P53924 | Ensembl Canonical, |