Major mitochondrial nuclease; has RNAse and DNA endo- and exonucleolytic activities; roles in mitochondrial recombination, apoptosis and maintenance of polyploidy; involved in fragmentation of genomic DNA during PND (programmed nuclear destruction); encodes ortholog of mammalian endoG [Source:SGD;Acc:S000003744]
Chromosome X: 40,194-41,183 reverse strand.
R64-1-1:BK006943.2
This gene has 1 transcript (splice variant) and 190 orthologues.
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YJL208C_mRNA | NUC1 | 990 | 329aa | YJL208C | Protein coding | P08466 | Ensembl Canonical, |