Pyruvate kinase; functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration; regulated via allosteric activation by fructose bisphosphate; CDC19 has a paralog, PYK2, that arose from the whole genome duplication [Source:SGD;Acc:S000000036]
PYK1
Chromosome I: 71,786-73,288 forward strand.
R64-1-1:BK006935.2
This gene has 1 transcript (splice variant), 533 orthologues and 1 paralogue.
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YAL038W_mRNA | CDC19 | 1503 | 500aa | YAL038W | Protein coding | P00549 | Ensembl Canonical, |