Description

potassium large conductance calcium-activated channel, subfamily M, alpha member 1 [Source:MGI Symbol;Acc:MGI:99923]

Location
INSDC coordinates

chromosome:GRCm38:CM001007.2:23289431:24004859:1

About this gene

This gene has 15 transcripts (splice variants), 81 orthologues, 3 paralogues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
Kcnma1-001ENSMUST0000018821049901209aaENSMUSP00000141069
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A0A087WSJ2 NM_001253369
NM_001253371
NP_001240298
NP_001240300
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT2

ALTERNATIVE2 - APPRIS candidate principal isoform that appears to be conserved in fewer than three tested non-primate species.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

Kcnma1-207ENSMUST0000017763446051135aaENSMUSP00000136447
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-J3QMT8 -TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
Kcnma1-208ENSMUST0000017909745961132aaENSMUSP00000136568
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-J3QN27 NM_001253358
NM_001253359
NM_001253360
NM_001253366
NP_001240287
NP_001240288
NP_001240289
NP_001240295
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
Kcnma1-201ENSMUST0000006578845241108aaENSMUSP00000065293
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-F6ZSN2 -TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
Kcnma1-003ENSMUST0000018828544401239aaENSMUSP00000140275
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A0A087WQN5 NM_001253361
NM_001253362
NM_001253363
NP_001240290
NP_001240291
NP_001240292
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P5

PRINCIPAL5 - APPRIS candidate principal isoform (longest coding sequence).

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

Kcnma1-202ENSMUST0000007498339741107aaENSMUSP00000074511
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-F6XW53 -TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT2

ALTERNATIVE2 - APPRIS candidate principal isoform that appears to be conserved in fewer than three tested non-primate species.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

Kcnma1-005ENSMUST0000019004437471178aaENSMUSP00000140033
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A0A087WQ41 NM_001253365
NM_001253367
NM_001253372
NM_001253376
NM_001253377
NM_001253378
NP_001240294
NP_001240296
NP_001240301
NP_001240305
NP_001240306
NP_001240307
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT2

ALTERNATIVE2 - APPRIS candidate principal isoform that appears to be conserved in fewer than three tested non-primate species.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

Kcnma1-006ENSMUST0000018899137111236aaENSMUSP00000140751
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A0A087WRS4 NM_001253364
NM_001253373
NM_010610
NP_001240293
NP_001240302
NP_034740
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT2

ALTERNATIVE2 - APPRIS candidate principal isoform that appears to be conserved in fewer than three tested non-primate species.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

Kcnma1-204ENSMUST0000011242336641055aaENSMUSP00000108042
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-F7BHL0 NM_001253374
NP_001240303
TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
Kcnma1-206ENSMUST0000017209933541118aaENSMUSP00000132204
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-F6WSZ3 -TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT2

ALTERNATIVE2 - APPRIS candidate principal isoform that appears to be conserved in fewer than three tested non-primate species.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

Kcnma1-203ENSMUST0000010083132611086aaENSMUSP00000098393
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-F6V0P5 NM_001253368
NM_001253370
NP_001240297
NP_001240299
TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
Kcnma1-209ENSMUST0000017983631771059aaENSMUSP00000137141
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-J3QP84 -TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
Kcnma1-205ENSMUST0000016332231621053aaENSMUSP00000128553
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E9Q9P4 NM_001253375
NP_001240304
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
Kcnma1-002ENSMUST00000190339890191aaENSMUSP00000141143
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-A0A087WSQ4 -TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
Kcnma1-004ENSMUST000001909853557650aaENSMUSP00000140154
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-A0A087WQE1 -CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays