complement factor B [Source:MGI Symbol;Acc:MGI:105975]
B, Bf, FB, Factor B, H2-Bf, alternative-complement pathway C3/C5 convertase
Chromosome 17: 35,075,350-35,081,494 reverse strand.
GRCm39:CM001010.3
This gene has 8 transcripts (splice variants), 196 orthologues, 37 paralogues and is associated with 21 phenotypes.
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | Flags |
|---|---|---|---|---|---|---|---|---|
| ENSMUST00000025229.11 | Cfb-201 | 2737 | 763aa | ENSMUSP00000025229.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS28663 | B8JJM5 | A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1, |
| ENSMUST00000128767.8 | Cfb-202 | 2751 | 761aa | ENSMUSP00000119977.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | P04186 Q3UEG8 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P4: Where the APPRIS core modules are unable to choose a clear principal CDS and there is more than one variant with a distinct (but consecutive) CCDS identifiers, APPRIS selects the longest CCDS isoform as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P4,TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1, | |
| ENSMUST00000176203.9 | Cfb-207 | 2733 | 713aa | ENSMUSP00000135660.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS50079 | B8JJM6 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1, |
| ENSMUST00000154526.8 | Cfb-206 | 2397 | 711aa | ENSMUSP00000120990.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F6XQ00 | The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1, | |
| ENSMUST00000141295.8 | Cfb-204 | 973 | 259aa | ENSMUSP00000118945.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | F6W2T4 | TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5, 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENSMUST00000176332.2 | Cfb-208 | 905 | 296aa | ENSMUSP00000135304.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | H3BK95 | TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5, 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENSMUST00000153400.8 | Cfb-205 | 887 | 234aa | ENSMUSP00000116497.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | B8JJM3 | TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5, 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, | |
| ENSMUST00000133127.2 | Cfb-203 | 655 | 81aa | ENSMUSP00000118360.2 | Nonsense mediated decay | F6WZA2 | TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5, 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, |
