Description

neurofibromin 2 (merlin) [Source:HGNC Symbol;Acc:HGNC:7773]

Synonyms

merlin

Location
Gene

This transcript is a product of gene ENSG00000186575

This gene has 11 transcripts (splice variants) Show transcript tableHide transcript table

NameTranscript IDbpProteinBiotypeCCDSUniProtRefSeqFlags
NF2-001ENST000003386416025595 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13861A0A024R1J8 P35240 Q9NRW8
NM_000268
NP_000259
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PIAPPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
NF2-010ENST000003614525884549 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13864A0A024R1F6 P35240 Q9NRW8
NM_181829
NP_861967
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
NF2-201ENST000004132094733165 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS54516P35240 Q9NRW8 NM_181833
NP_861971
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
NF2-003ENST000004039992999590 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13862A0A024R1J9 P35240 Q9NRW8
NM_181825
NP_861546
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
NF2-008ENST000003349612020507 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13865A0A024R1D9 P35240 Q9NRW8
NM_181831
NP_861969
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
NF2-009ENST000003977891857590 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13862A0A024R1J9 P35240 Q9NRW8
NM_181832
NP_861970
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
NF2-005ENST000003538871845507 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13865A0A024R1D9 P35240 Q9NRW8
NM_181830
NP_861968
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
NF2-007ENST000003611661837590 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13862A0A024R1J9 P35240 Q9NRW8
NM_016418
NP_057502
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
NF2-006ENST000003616761716548 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13863A0A024R1I0 P35240 Q9NRW8
NM_181828
NP_861966
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
NF2-004ENST000004034352568561 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-P35240 Q9NRW8 -TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
NF2-002ENST000004321511000220 aa
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-P35240 Q9NRW8 -TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 15 Coding exons: 14 Transcript length: 1,845 bps Translation length: 507 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS13865

Uniprot

This transcript corresponds to the following Uniprot identifiers: P35240

Transcript Support Level

1

Ensembl version

ENST00000353887.6

Type

Known protein coding

Prediction Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays