Description

PDZ binding kinase [Source:HGNC Symbol;Acc:HGNC:18282]

Synonyms

CT84, FLJ14385, Nori-3, SPK, TOPK

Location
About this transcript

This transcript has 8 exons, is annotated with 7 domains and features, is associated with 87 variations and maps to 9 oligo probes.

Gene
NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
PBK-001ENST000003019052118322aaENSP00000301905
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS6063Q96KB5 V9HWH0 NM_018492
NP_060962
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
PBK-002ENST000005229441499333aaENSP00000428489
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS64858Q96KB5 NM_001278945
NP_001265874
TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
PBK-005ENST00000521226748151aaENSP00000427892
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-E5RFX4 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

PBK-006ENST0000052426681963aaENSP00000428438
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-E5RIE1 -TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 8 Coding exons: 7 Transcript length: 2,118 bps Translation length: 322 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS6063

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q96KB5

Transcript Support Level (TSL)

TSL:1

Ensembl version

ENST00000301905.7

Type

Known protein coding

Annotation Method

Transcript where the Ensembl genebuild transcript and the Vega manual annotation have the same sequence, for every base pair. See article.

Alternative transcripts

This transcript corresponds to the following database identifiers:

Havana transcript:
GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays