Description

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) [Source:HGNC Symbol;Acc:HGNC:9604]

Synonyms

COX1, PGHS-1, PTGHS

Gene

This transcript is a product of gene ENSG00000095303

This gene has 7 transcripts (splice variants) Show transcript tableHide transcript table

NameTranscript IDbpProteinBiotypeCCDSUniProtRefSeqFlags
PTGS1-202ENST000005407535375537 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS59520P23219 NM_001271368
NP_001258297
TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
PTGS1-201ENST000003736984987490 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS59521P23219 NM_001271165
NM_001271166
NM_001271367
NP_001258094
NP_001258095
NP_001258296
TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
PTGS1-001ENST000003620124964599 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS6842P23219 NM_000962
NP_000953
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS CI3APPRIS candidate principal isoform (CCDS)
Glossary entry for APPRIS
APPRIS website
PTGS1-203ENST000006149104894551 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS75895-NM_001271164
NP_001258093
TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
PTGS1-002ENST000002234232328562 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS6843P23219 NM_080591
NP_542158
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
PTGS1-204ENST000006193065051630 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-P23219 -TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS CIAPPRIS candidate principal isoform
Glossary entry for APPRIS
APPRIS website
PTGS1-003ENST00000426608468156 aa
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-X6RJD6 -CDS 5' and 3' incomplete5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Statistics

Exons: 10 Coding exons: 8 Transcript length: 4,987 bps Translation length: 490 residues

CCDS

This transcript is a member of the Human CCDS set: CCDS59521

Uniprot

This transcript corresponds to the following Uniprot identifiers: P23219

Transcript Support Level

2

Ensembl version

ENST00000373698.6

Type

Known protein coding

Prediction Method

Annotation produced by the Ensembl genebuild.

GENCODE basic gene

This transcript is a member of the Gencode basic gene set.

Transcript-based displays