Description

beta-site APP-cleaving enzyme 1 [Source:HGNC Symbol;Acc:HGNC:933]

Synonyms

BACE

Location

Chromosome 11: 117,285,207-117,316,259 reverse strand.

GRCh38:CM000673.2

About this gene

This gene has 12 transcripts (splice variants), 67 orthologues, 10 paralogues, is a member of 3 Ensembl protein families and is associated with 56 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
BACE1-001ENST000003130056326501aaENSP00000318585
 
Protein coding
CCDS8383A0A024R3D7 P56817 NM_012104
NP_036236
TSL:1GENCODE basicAPPRIS P1
BACE1-006ENST000003929375155401aaENSP00000475405
 
Protein coding
CCDS55787B7Z3Z4 P56817 NM_001207048
NP_001193977
TSL:1GENCODE basic
BACE1-003ENST000005137801465476aaENSP00000424536
 
Protein coding
CCDS44739A0A024R3E8 P56817 NM_138972
NP_620428
TSL:1GENCODE basic
BACE1-004ENST000004458231408457aaENSP00000403685
 
Protein coding
CCDS44740A0A024R3D5 P56817 NM_138971
NP_620427
TSL:1GENCODE basic
BACE1-002ENST000004283811333432aaENSP00000402228
 
Protein coding
CCDS44741A0A024R3F9 P56817 NM_138973
NP_620429
TSL:1GENCODE basic
BACE1-007ENST000005106301236376aaENSP00000422461
 
Protein coding
CCDS55786B7Z3K2 P56817 NM_001207049
NP_001193978
TSL:2GENCODE basic
BACE1-013ENST000005280534083467aaENSP00000431848
 
Protein coding
-E9PJG7 -TSL:5GENCODE basic
BACE1-008ENST0000050499561140aaENSP00000434486
 
Protein coding
-H0YDX0 -CDS 3' incompleteTSL:3
BACE1-009ENST0000051091556151aaENSP00000475171
 
Protein coding
-U3KPS1 -CDS 3' incompleteTSL:5
BACE1-005ENST00000514464517No protein-
 
Processed transcript
---TSL:2
BACE1-016ENST00000530824984No protein-
 
Retained intron
---TSL:2
BACE1-010ENST00000509916593No protein-
 
Retained intron
---TSL:3

Gene-based displays