Description

flap structure-specific endonuclease 1 [Source:HGNC Symbol;Acc:HGNC:3650]

Synonyms

FEN-1, MF1, RAD2

Location
INSDC coordinates

chromosome:GRCh38:CM000673.2:61792637:61797244:1

About this gene

This gene has 3 transcripts (splice variants), 61 orthologues, 1 paralogue, is a member of 1 Ensembl protein family and is associated with 33 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
FEN1-001ENST000003058852296380aaENSP00000305480
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS8010P39748 Q6FHX6 NM_004111
NP_004102
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI1APPRIS principal isoform
Glossary entry for APPRIS
APPRIS website
FEN1-003ENST00000535723776165aaENSP00000445692
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-F5H1Y3 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

FEN1-004ENST00000535307768154aaENSP00000460402
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-I3L3E9 -CDS 5' incomplete5' truncation in transcript evidence prevents annotation of the start of the CDS.TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays