Description

thyroid hormone receptor, beta [Source:HGNC Symbol;Acc:HGNC:11799]

Synonyms

ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR1, THRB1, THRB2

Location
INSDC coordinates

chromosome:GRCh38:CM000665.2:24117160:24495282:1

About this gene

This gene has 12 transcripts (splice variants), 68 orthologues, 18 paralogues, is a member of 3 Ensembl protein families and is associated with 6 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
THRB-201ENST000003966717506461aaENSP00000379904
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS2641F1D8N7 P10828 NM_001128176
NP_001121648
TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI2APPRIS candidate principal isoform (CCDS)
Glossary entry for APPRIS
APPRIS website
THRB-001ENST000003564476345461aaENSP00000348827
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS2641F1D8N7 P10828 NM_000461
NM_001128177
NP_000452
NP_001121649
TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI2APPRIS candidate principal isoform (CCDS)
Glossary entry for APPRIS
APPRIS website
THRB-004ENST000004164202571461aaENSP00000414444
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS2641F1D8N7 P10828 NM_001252634
NP_001239563
TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS PI2APPRIS candidate principal isoform (CCDS)
Glossary entry for APPRIS
APPRIS website
THRB-003ENST000002806961718476aaENSP00000280696
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-P10828 -TSL:5

TSL5: No single transcript (mRNA or EST) supports this transcript model's structure.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS ALT1APPRIS candidate principal isoform that is conserved in at least three tested non-primate species
Glossary entry for APPRIS
APPRIS website
THRB-011ENST00000413780896132aaENSP00000414100
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-C9JNQ4 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:3

TSL3:The only support for this transcript is from a single EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

THRB-006ENST00000447875754122aaENSP00000388467
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-P10828 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

THRB-002ENST00000453729703121aaENSP00000414910
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-J3KR21 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

THRB-005ENST00000415021671122aaENSP00000404898
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-P10828 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

THRB-012ENST0000041824759263aaENSP00000393932
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-C9JZS5 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:2

TSL2: The best supporting mRNA is flagged as suspect or the support is from multiple ESTs.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

THRB-010ENST00000447414575103aaENSP00000399573
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-C9JTN1 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

THRB-008ENST00000431815568114aaENSP00000395362
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-C9JJM3 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:1

TSL1: All splice junctions of the transcript are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

THRB-009ENST0000042849253967aaENSP00000404233
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-C9JHC2 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:4

TSL4:The best supporting EST for this transcript is flagged as suspect.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays