Description

MDM2 proto-oncogene, E3 ubiquitin protein ligase [Source:HGNC Symbol;Acc:HGNC:6973]

Synonyms

HDM2, MGC5370

Location

Chromosome 12: 68,808,172-68,850,686 forward strand.

GRCh38:CM000674.2

About this gene

This gene has 36 transcripts (splice variants), 74 orthologues, 1 paralogue, is a member of 11 Ensembl protein families and is associated with 3 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
MDM2-001ENST0000025814912633497aaENSP00000258149
 
Protein coding
CCDS8986Q00987 NM_002392
NP_002383
TSL:1GENCODE basicAPPRIS P2
MDM2-201ENST000003562906735321aaENSP00000348637
 
Protein coding
CCDS61189Q00987 NM_001145340
NM_001278462
NP_001138812
NP_001265391
TSL:1GENCODE basic
MDM2-006ENST00000299252966321aaENSP00000299252
 
Protein coding
CCDS61189Q00987 -TSL:1GENCODE basic
MDM2-204ENST000004622847420466aaENSP00000417281
 
Protein coding
-J3KN53 -TSL:5GENCODE basic
MDM2-202ENST000003934121404243aaENSP00000377064
 
Protein coding
-Q9H4C5 -TSL:5GENCODE basic
MDM2-033ENST000003500571401466aaENSP00000266624
 
Protein coding
-J3KN53 -TSL:1GENCODE basic
MDM2-003ENST000002581481361442aaENSP00000258148
 
Protein coding
-G3XA89 NM_001145339
NP_001138811
TSL:1GENCODE basicAPPRIS ALT2
MDM2-203ENST000004288631037243aaENSP00000410694
 
Protein coding
-Q8TE47 -TSL:5GENCODE basic
MDM2-008ENST00000360430891296aaENSP00000353611
 
Protein coding
-Q00987 -TSL:1GENCODE basic
MDM2-012ENST00000539479845257aaENSP00000444430
 
Protein coding
-A7UKY0 -CDS 3' incompleteTSL:1
MDM2-022ENST00000393415842256aaENSP00000377067
 
Protein coding
-A7UKX8 NM_001145337
NP_001138809
CDS 3' incompleteTSL:5
MDM2-009ENST00000348801798265aaENSP00000335096
 
Protein coding
-A0A0C4DFR5 -TSL:1GENCODE basic
MDM2-013ENST00000393416754229aaENSP00000377068
 
Protein coding
-E7EPE2 -CDS 3' incompleteTSL:5
MDM2-004ENST00000393410732243aaENSP00000377062
 
Protein coding
-Q9H4C5 -TSL:1GENCODE basic
MDM2-011ENST0000047807069249aaENSP00000430906
 
Protein coding
-E5RHE2 -TSL:1GENCODE basic
MDM2-032ENST00000393413657218aaENSP00000377065
 
Protein coding
-Q00987 -TSL:1GENCODE basic
MDM2-016ENST00000523991505144aaENSP00000427828
 
Protein coding
-E7EMW5 -CDS 3' incompleteTSL:1
MDM2-023ENST00000543323427118aaENSP00000439238
 
Protein coding
-A0A0A6YYM9 A7UKX7 -CDS 3' incompleteTSL:1
MDM2-024ENST0000054520439851aaENSP00000444597
 
Protein coding
-F5GZB0 -TSL:5GENCODE basic
MDM2-019ENST00000517852393130aaENSP00000430257
 
Protein coding
-Q9H4C3 -TSL:1GENCODE basic
MDM2-026ENST0000054456121370aaENSP00000441841
 
Protein coding
-F5GWH7 -TSL:5GENCODE basic
MDM2-002ENST00000393417168370aaENSP00000429021
 
Nonsense mediated decay
-Q8NDW1 -TSL:5
MDM2-010ENST00000311420158384aaENSP00000310742
 
Nonsense mediated decay
-J3QST1 -TSL:5
MDM2-028ENST000005403521315170aaENSP00000445030
 
Nonsense mediated decay
-F5H4Q8 -TSL:1
MDM2-031ENST00000536089118178aaENSP00000444028
 
Nonsense mediated decay
-F5H1M7 -TSL:1
MDM2-029ENST00000542502112784aaENSP00000444566
 
Nonsense mediated decay
-F5GZC3 -TSL:1
MDM2-007ENST00000481186105635aaENSP00000431110
 
Nonsense mediated decay
-E5RJQ0 -TSL:5
MDM2-030ENST00000537182101178aaENSP00000443450
 
Nonsense mediated decay
-F5H1M7 -TSL:1
MDM2-005ENST0000049695989760aaENSP00000429692
 
Nonsense mediated decay
-Q96DS5 -TSL:1
MDM2-027ENST0000054604836378aaENSP00000445222
 
Nonsense mediated decay
-F5H1M7 -TSL:5
MDM2-043ENST00000544125649No protein-
 
Processed transcript
---TSL:2
MDM2-042ENST00000540709502No protein-
 
Processed transcript
---TSL:3
MDM2-044ENST00000400501406No protein-
 
Processed transcript
---TSL:2
MDM2-015ENST00000493419577No protein-
 
Retained intron
---TSL:2
MDM2-041ENST00000543046432No protein-
 
Retained intron
---TSL:3
MDM2-014ENST00000471946251No protein-
 
Retained intron
---TSL:3

Gene-based displays