Description

hepatocyte nuclear factor 4, alpha [Source:HGNC Symbol;Acc:HGNC:5024]

Synonyms

HNF4, MODY, MODY1, NR2A1, TCF14

Location
INSDC coordinates

chromosome:GRCh38:CM000682.2:44355700:44434596:1

About this gene

This gene has 9 transcripts (splice variants), 47 orthologues, 11 paralogues, is a member of 2 Ensembl protein families and is associated with 8 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
HNF4A-002ENST000003160996445474aaENSP00000312987
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13330F1D8T1 P41235 NM_000457
NM_001258355
NP_000448
NP_001245284
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).APPRIS P1

PRINCIPAL1 - APPRIS candidate principal isoform.

APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods.

HNF4A-201ENST000006195504763449aaENSP00000481331
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS74728A0A087WXV4 NM_001287182
NM_001287183
NP_001274111
NP_001274112
TSL:5

Transcript Support Level 5, for transcripts that are not supported at all by either an mRNA or an EST.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
HNF4A-006ENST000004156912302464aaENSP00000412111
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS46605F1D8S2 P41235 NM_178849
NP_849180
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
HNF4A-004ENST000004435981603417aaENSP00000410911
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS13331P41235 NM_178850
NP_849181
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
HNF4A-001ENST000003166731470452aaENSP00000315180
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS42876F1D8T0 P41235 NM_175914
NP_787110
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
HNF4A-005ENST000004572321339442aaENSP00000396216
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS46604P41235 NM_001030003
NP_001025174
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
HNF4A-007ENST000006097951192395aaENSP00000476609
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
CCDS68131P41235 NM_001030004
NM_001287184
NP_001025175
NP_001274113
TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

GENCODE basicThe GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).
HNF4A-008ENST00000609262540103aaENSP00000476310
 
Protein codingGenes and/or transcript that contains an open reading frame (ORF).
-B9VVT8 -CDS 3' incomplete3' truncation in transcript evidence prevents annotation of the end of the CDS.TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

HNF4A-003ENST000003729203340107aaENSP00000362011
 
Nonsense mediated decayTranscript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins.
-F8WBS7 -TSL:1

Transcript Support Level 1, when transcripts are supported by at least one non-suspect mRNA.

The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users. The method relies on the primary data that can support full-length transcript structure: mRNA and EST alignments supplied by UCSC and Ensembl.

Gene-based displays