Description

apurinic/apyrimidinic endodeoxyribonuclease 1 [Source:HGNC Symbol;Acc:HGNC:587]

Synonyms

APX, REF1, APE-1, HAP1, APEX, REF-1, APEN, APE

Location

Chromosome 14: 20,455,191-20,457,772 forward strand.

GRCh38:CM000676.2

About this gene

This gene has 20 transcripts (splice variants), 88 orthologues, 1 paralogue, is a member of 1 Ensembl protein family and is associated with 7 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
APEX1-201ENST00000216714.71484318aaENSP00000216714
 
Protein coding
CCDS9550P27695 Q5TZP7 NM_001244249
NM_001641
NP_001231178
NP_001632
TSL:1GENCODE basicAPPRIS P1
APEX1-210ENST00000555414.51437318aaENSP00000451979
 
Protein coding
CCDS9550P27695 Q5TZP7 NM_080648
NM_080649
NP_542379
NP_542380
TSL:1GENCODE basicAPPRIS P1
APEX1-202ENST00000398030.81387318aaENSP00000381111
 
Protein coding
CCDS9550P27695 Q5TZP7 -TSL:1GENCODE basicAPPRIS P1
APEX1-211ENST00000555839.5952242aaENSP00000452460
 
Protein coding
-G3V5Q1 -CDS 3' incompleteTSL:2
APEX1-206ENST00000553681.5899263aaENSP00000451327
 
Protein coding
-G3V3M6 -CDS 3' incompleteTSL:3
APEX1-214ENST00000557054.188814aaENSP00000452212
 
Protein coding
-G3V574 -TSL:5GENCODE basic
APEX1-212ENST00000556054.5773174aaENSP00000451170
 
Protein coding
-G3V3C7 -CDS 3' incompleteTSL:3
APEX1-215ENST00000557150.5740162aaENSP00000452418
 
Protein coding
-G3V5M0 -CDS 3' incompleteTSL:3
APEX1-218ENST00000557344.5671146aaENSP00000452137
 
Protein coding
-A0A0C4DGK8 -CDS 3' incompleteTSL:2
APEX1-220ENST00000557592.5640172aaENSP00000451060
 
Protein coding
-G3V359 -CDS 3' incompleteTSL:5
APEX1-217ENST00000557181.5566107aaENSP00000452304
 
Protein coding
-G3V5D9 -CDS 3' incompleteTSL:3
APEX1-203ENST00000438886.1451150aaENSP00000416414
 
Protein coding
-H7C4A8 -CDS 5' and 3' incompleteTSL:3
APEX1-204ENST00000553368.130441aaENSP00000451491
 
Protein coding
-G3V3Y6 -CDS 3' incompleteTSL:3
APEX1-207ENST00000554325.156849aaENSP00000450604
 
Nonsense mediated decay
-G3V2D9 -TSL:5
APEX1-219ENST00000557365.1831No protein-
 
Processed transcript
---TSL:3
APEX1-208ENST00000554813.5654No protein-
 
Processed transcript
---TSL:3
APEX1-213ENST00000556296.1571No protein-
 
Processed transcript
---TSL:4
APEX1-216ENST00000557159.51803No protein-
 
Retained intron
---TSL:2
APEX1-205ENST00000553555.51603No protein-
 
Retained intron
---TSL:1
APEX1-209ENST00000555306.5898No protein-
 
Retained intron
---TSL:5

Gene-based displays