Description

caspase 8, apoptosis-related cysteine peptidase [Source:HGNC Symbol;Acc:HGNC:1509]

Synonyms

Casp-8, FLICE, MACH, MCH5

Location

Chromosome 2: 201,233,443-201,287,711 forward strand.

GRCh38:CM000664.2

About this gene

This gene has 20 transcripts (splice variants), 64 orthologues, 12 paralogues, is a member of 3 Ensembl protein families and is associated with 3 phenotypes.

NameTranscript IDbpProteinTranslation IDBiotypeCCDSUniProtRefSeqFlags
CASP8-002ENST000003584852930538aaENSP00000351273
 
Protein coding
CCDS42798Q14790 NM_001080125
NP_001073594
TSL:1GENCODE basicAPPRIS P4
CASP8-012ENST000003234922650464aaENSP00000325722
 
Protein coding
CCDS2343A0A024R3Z8 Q14790 NM_033356
NP_203520
TSL:1GENCODE basicAPPRIS ALT2
CASP8-006ENST000002642751906496aaENSP00000264275
 
Protein coding
CCDS42799Q14790 NM_001228
NP_001219
TSL:1GENCODE basicAPPRIS ALT2
CASP8-009ENST000003922631630464aaENSP00000376091
 
Protein coding
CCDS2343A0A024R3Z8 Q14790 NM_001080124
NP_001073593
CDS 3' incompleteTSL:5
CASP8-014ENST000004321091629479aaENSP00000412523
 
Protein coding
CCDS2342Q14790 NM_033355
NP_203519
TSL:5GENCODE basicAPPRIS ALT2
CASP8-004ENST000003922581060235aaENSP00000376087
 
Protein coding
CCDS2345Q14790 NM_033358
NP_203522
TSL:1GENCODE basic
CASP8-201ENST000002642742540395aaENSP00000264274
 
Protein coding
-Q14790 -TSL:5GENCODE basic
CASP8-202ENST000003922661283278aaENSP00000376094
 
Protein coding
-A0A0A0MS31 -TSL:2GENCODE basic
CASP8-017ENST000004444301275258aaENSP00000394434
 
Protein coding
-H7C0E2 -CDS 5' incompleteTSL:5
CASP8-026ENST00000429881717116aaENSP00000390641
 
Protein coding
-E7EQ01 -CDS 3' incompleteTSL:3
CASP8-010ENST00000447616707209aaENSP00000388306
 
Protein coding
-E7EQ06 -CDS 3' incompleteTSL:5
CASP8-020ENST00000450491686149aaENSP00000391709
 
Protein coding
-C9JB29 -CDS 3' incompleteTSL:3
CASP8-023ENST00000413726658198aaENSP00000397528
 
Protein coding
-E7ETB7 -CDS 3' incompleteTSL:5
CASP8-021ENST00000440732592124aaENSP00000396869
 
Protein coding
-E7EVN1 -CDS 3' incompleteTSL:4
CASP8-016ENST0000042446130883aaENSP00000390346
 
Protein coding
-H7BZM4 -CDS 5' incompleteTSL:5
CASP8-001ENST0000043728377758aaENSP00000407378
 
Nonsense mediated decay
-F8WF39 -TSL:1
CASP8-008ENST000004906822911No protein-
 
Processed transcript
---TSL:1
CASP8-011ENST00000490412230No protein-
 
Processed transcript
---TSL:1
CASP8-007ENST000003394031723No protein-
 
Retained intron
---TSL:1
CASP8-015ENST00000471383969No protein-
 
Retained intron
---TSL:1

Gene-based displays