Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: KL ENSDARG00000079862

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Description

klotho [Source:HGNC Symbol;Acc:HGNC:6344]

Location

Chromosome 10: 34,001,444-34,026,125 forward strand.

GRCz11:CM002894.2

About this gene

This gene has 3 transcripts (splice variants), 202 orthologues, 6 paralogues and is associated with 28 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSDART00000114703.4	KL-203	7449	990aa	ENSDARP00000100445.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	F1RC43	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P5: Where the APPRIS core modules are unable to choose a clear principal variant and none of the candidate variants are annotated by CCDS, APPRIS selects the longest of the candidate isoforms as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P5,
ENSDART00000186836.1	KL-202	7341	937aa	ENSDARP00000148269.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	-	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSDART00000149934.3	KL-201	3591	990aa	ENSDARP00000124944.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	F1RC43	APPRIS P5: Where the APPRIS core modules are unable to choose a clear principal variant and none of the candidate variants are annotated by CCDS, APPRIS selects the longest of the candidate isoforms as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P5,

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Summary

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