Major isoform of large subunit of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits; relative distribution to the nucleus increases upon DNA replication stress; RNR1 has a paralog, RNR3, that arose from the whole genome duplication [Source:SGD;Acc:S000000872]
CRT7, RIR1, SDS12
Chromosome V: 298,950-301,616 forward strand.
This transcript has 1 exon, is annotated with 23 domains and features, is associated with 28 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YER070W Show transcript tableHide transcript table
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YER070W_mRNA | RNR1 | 2667 | 888aa | YER070W | Protein coding | P21524 | Ensembl Canonical, |