5-aminolevulinate synthase; catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p; has a pyridoxal phosphate cofactor whose insertion is mediated by Mcx1p [Source:SGD;Acc:S000002640]
CYD1, OLE3
Chromosome IV: 927,452-929,098 forward strand.
R64-1-1:BK006938.2
This gene has 1 transcript (splice variant), 196 orthologues and 2 paralogues.
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YDR232W_mRNA | HEM1 | 1647 | 548aa | YDR232W | Protein coding | P09950 | Ensembl Canonical, |