Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
- Variant table
- Variant image
- Structural variants
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: APH1A ENSPTRG00000001250

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Description

aph-1 homolog A, gamma-secretase subunit [Source:VGNC Symbol;Acc:VGNC:91]

Location

Chromosome 1: 128,194,901-128,211,790 reverse strand.

Pan_tro_3.0:CM000314.3

About this gene

This gene has 4 transcripts (splice variants), 137 orthologues and 1 paralogue.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSPTRT00000050506.5	APH1A-202	1922	265aa	ENSPTRP00000043775.4	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A6D2WJP4 H2R2D2	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P5: Where the APPRIS core modules are unable to choose a clear principal variant and none of the candidate variants are annotated by CCDS, APPRIS selects the longest of the candidate isoforms as the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P5,
ENSPTRT00000087107.1	APH1A-203	2291	149aa	ENSPTRP00000073216.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3S8Q5	-
ENSPTRT00000081231.1	APH1A-204	2064	247aa	ENSPTRP00000089295.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A6D2XEB6 G2HHW2	APPRIS ALT1: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that is conserved in at least three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT1,
ENSPTRT00000088812.1	APH1A-201	1531	195aa	ENSPTRP00000075979.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A2I3SG11 A0A6D2XK35	-

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Summary

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