Gene: Serpina1a ENSMUSG00000066366

Description

serine (or cysteine) peptidase inhibitor, clade A, member 1A [Source:MGI Symbol;Acc:MGI:891971]

Gene Synonyms

Aat-2, Aat2, PI1, Spi1-1

Location

Chromosome 12: 103,819,848-103,829,821 reverse strand.

GRCm39:CM001005.3

About this gene

This gene has 3 transcripts (splice variants), 119 orthologues, 63 paralogues and is associated with 2 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000072876.12	Serpina1a-201	1581	436aa	ENSMUSP00000072652.7	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS79152	A0A0A0MQA3	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000085056.8	Serpina1a-202	1360	413aa	ENSMUSP00000082132.7	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS26140	P07758	The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000124717.2	Serpina1a-203	578	96aa	ENSMUSP00000120398.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		D3YZL0	TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,