Gene: Mdc1 ENSMUSG00000061607

Description

mediator of DNA damage checkpoint 1 [Source:MGI Symbol;Acc:MGI:3525201]

Gene Synonyms

NFBD1

Location

Chromosome 17: 36,152,407-36,170,562 forward strand.

GRCm39:CM001010.3

About this gene

This gene has 3 transcripts (splice variants), 179 orthologues, 1 paralogue and is associated with 16 phenotypes.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000082337.13	Mdc1-201	7335	1708aa	ENSMUSP00000080949.7	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS37604	E9QK89	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 5: A transcript where no single transcript supports the model structure. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:5,
ENSMUST00000225192.2	Mdc1-203	649	216aa	ENSMUSP00000153197.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A286YCY4	5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete,
ENSMUST00000174124.2	Mdc1-202	422	109aa	ENSMUSP00000133568.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		G3UX64	TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:2, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,