Gene: Mapkapk2 ENSMUSG00000016528

Description

MAP kinase-activated protein kinase 2 [Source:MGI Symbol;Acc:MGI:109298]

Gene Synonyms

MAPKAP kinase 2, MK2, Rps6kc1

Location

Chromosome 1: 130,981,437-131,025,563 reverse strand.

GRCm39:CM000994.3

About this gene

This gene has 2 transcripts (splice variants), 233 orthologues, 6 paralogues and is associated with 33 phenotypes.

Transcripts

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Transcript ID	Name	bp	Protein	Translation ID	Biotype	CCDS	UniProt Match	Flags
ENSMUST00000016672.11	Mapkapk2-201	2854	386aa	ENSMUSP00000016672.5	Gene/transcipt that contains an open reading frame (ORF).Protein coding	CCDS15266	P49138 Q3U2P8	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, The GENCODE set is the gene set for human and mouse. GENCODE Basic is a subset of representative transcripts (splice variants).GENCODE basic, APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P1, TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA. The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:1,
ENSMUST00000188459.4	Mapkapk2-202	675	162aa	ENSMUSP00000141124.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding		A0A087WSN7	TSL 3: A transcript where the only support is from a single EST The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript. TSL:3, 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete,