Summary
- Splice variants
- Transcript comparison
- Gene alleles
Sequence
- Secondary Structure
Comparative Genomics
Ontologies
Phenotypes
Genetic Variation
Gene expression
Pathway
Molecular interactions
Regulation
External references
Supporting evidence
ID History
- Gene history

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Gene: SPAST ENSBTAG00000021694

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Description

spastin [Source:VGNC Symbol;Acc:VGNC:35174]

Location

Primary_assembly 11: 14,696,392-14,751,826 forward strand.

ARS-UCD1.3:CM008178.2

About this gene

This gene has 5 transcripts (splice variants), 235 orthologues, 9 paralogues and is associated with 1 phenotype.

Transcripts

Show transcript tableHide transcript table

Transcript ID	Name	bp	Protein	Translation ID	Biotype	UniProt Match	Flags
ENSBTAT00000046919.4	SPAST-202	3388	614aa	ENSBTAP00000044166.3	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A2VDN5	A single transcript chosen for a gene which is the most conserved, most highly expressed, has the longest coding sequence and is represented in other key resources, such as NCBI and UniProt. This is defined in detail on http://www.ensembl.org/info/genome/genebuild/canonical.htmlEnsembl Canonical, APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS P2,
ENSBTAT00000077648.2	SPAST-203	3388	614aa	ENSBTAP00000057028.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A3Q1MRP0	-
ENSBTAT00000069887.2	SPAST-204	3292	582aa	ENSBTAP00000058511.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A3Q1LWY3 A2VDN5	APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species. APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene. APPRIS ALT2,
ENSBTAT00000075299.2	SPAST-205	3131	557aa	ENSBTAP00000072889.1	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A3Q1MNP4	-
ENSBTAT00000067878.2	SPAST-201	2237	602aa	ENSBTAP00000074249.2	Gene/transcipt that contains an open reading frame (ORF).Protein coding	A0A3Q1MR97	-

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Summary

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