Description
Outer kinetochore protein, needed for accurate chromosome segregation; component of kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as platform for kinetochore assembly; required for spindle assembly checkpoint; minimizes potentially deleterious centromere-proximal crossovers by preventing meiotic DNA break formation proximal to centromere; homolog of human centromere constitutive-associated network (CCAN) subunit CENP-P and fission yeast fta2 [Source:SGD;Acc:S000005939]
Gene Synonyms
MCM18
Location
Chromosome XVI: 517,651-518,760 forward strand.
R64-1-1:BK006949.2
About this gene
This gene has 1 transcript (splice variant).
Transcripts
