Description
Alpha-arrestin involved in ubiquitin-dependent endocytosis; regulates endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its targets; involved in the basal internalization and turnover of alpha-factor receptor Ste2p; recruits ubiquitin ligase Rsp5p to Ste2p via its 2 PPXY motifs; inhibited by Npr1p-mediated phosphorylation, which affects translocation between the cytosol and the plasma membrane [Source:SGD;Acc:S000005849]
Gene Synonyms
ART1
Location
Chromosome XV: 918,606-921,062 reverse strand.
R64-1-1:BK006948.2
About this gene
This gene has 1 transcript (splice variant).
Transcripts
