Description
Origin-binding F-box protein; forms SCF ubiquitin ligase complex with Skp1p and Cdc53p; functions in ubiquitination of silent chromatin structural protein Sir4p; required to target Cdc6p for destruction during G1 phase; required for deactivation of Rad53 checkpoint kinase, completion of DNA replication during recovery from DNA damage, assembly of RSC complex, RSC-mediated transcription regulation, and nucleosome positioning; involved in invasive and pseudohyphal growth [Source:SGD;Acc:S000005606]
Gene Synonyms
YOR29-31
Location
Chromosome XV: 474,594-476,792 forward strand.
R64-1-1:BK006948.2
About this gene
This gene has 1 transcript (splice variant).
Transcripts
