Description
5'-3' exonuclease and flap-endonuclease; involved in recombination, double-strand break repair, MMS2 error-free branch of the post replication (PRR) pathway and DNA mismatch repair; role in telomere maintenance; member of the Rad2p nuclease family, with conserved N and I nuclease domains; relative distribution to the nucleus increases upon DNA replication stress; EXO1 has a paralog, DIN7, that arose from the whole genome duplication [Source:SGD;Acc:S000005559]
Gene Synonyms
DHS1
Location
Chromosome XV: 392,416-394,524 reverse strand.
R64-1-1:BK006948.2
About this gene
This gene has 1 transcript (splice variant), 201 orthologues and 3 paralogues.
Transcripts
