Description
Non-canonical poly(A) polymerase; involved in nuclear RNA degradation as a component of TRAMP; catalyzes polyadenylation of hypomodified tRNAs, and snoRNA and rRNA precursors; required for mRNA surveillance and maintenance of genome integrity, serving as a link between RNA and DNA metabolism; overlapping but non-redundant functions with Trf5p; relocalizes to cytosol in response to hypoxia [Source:SGD;Acc:S000005475]
Gene Synonyms
TRF4
Location
Chromosome XV: 101,475-103,229 forward strand.
R64-1-1:BK006948.2
About this gene
This gene has 1 transcript (splice variant), 474 orthologues and 1 paralogue.
Transcripts
