Description
Protein that binds to DNA mismatches; forms heterodimers with Msh3p and Msh6p that bind to DNA mismatches to initiate the mismatch repair process; contains a Walker ATP-binding motif required for repair activity and involved in interstrand cross-link repair; Msh2p-Msh6p binds to and hydrolyzes ATP [Source:SGD;Acc:S000005450]
Gene Synonyms
PMS5
Location
Chromosome XV: 147,382-150,276 forward strand.
R64-1-1:BK006948.2
About this gene
This gene has 1 transcript (splice variant), 218 orthologues and 4 paralogues.
Transcripts
