Protein involved in 2'-O-methylation of C32 of substrate tRNAs; interacts with 2'-O-ribose methyltransferase Trm7p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; non-essential gene; yeast null mutant can be functionally complemented by human THADA, mutations in which have been implicated in epithelial thyroid adenomas, type 2 diabetes, and polycystic ovary syndrome (PCOS) [Source:SGD;Acc:S000004872]
Chromosome XIII: 784,621-788,883 reverse strand.
R64-1-1:BK006946.2
This gene has 1 transcript (splice variant) and 201 orthologues.
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YMR259C_mRNA | TRM732 | 4263 | 1420aa | YMR259C | Protein coding | Q03496 | Ensembl Canonical, |