Description
Subunit of telomeric Ku complex (Yku70p-Yku80p); involved in telomere length maintenance, structure and telomere position effect; required for localization of telomerase ribonucleoprotein via interaction with TLC1 guide RNA; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair; colocalizes with quiescent cell telomere hyperclusters [Source:SGD;Acc:S000004712]
Gene Synonyms
HDF2
Location
Chromosome XIII: 478,301-480,190 reverse strand.
R64-1-1:BK006946.2
About this gene
This gene has 1 transcript (splice variant), 201 orthologues and 1 paralogue.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
|---|---|---|---|---|---|---|---|
| YMR106C_mRNA | YKU80 | 1890 | 629aa | YMR106C | Protein coding | Q04437 | Ensembl Canonical, |
