Description
Actin cortical patch component; interacts with the actin depolymerizing factor cofilin; inhibits elongation of aged ADP-actin filaments decorated with cofilin to maintain a high level of assembly-competent actin species; required to restrict cofilin localization to cortical patches; putative regulator of cytokinesis; contains WD repeats; protein increases in abundance and relocalizes from cytoplasm to plasma membrane upon DNA replication stress [Source:SGD;Acc:S000004698]
Location
Chromosome XIII: 451,632-453,479 reverse strand.
R64-1-1:BK006946.2
About this gene
This gene has 1 transcript (splice variant) and 214 orthologues.
Transcripts
