Description
Inner nuclear membrane protein; highly enriched at telomeres and subtelomeric regions; functions in regulation of subtelomeric genes and is linked to TREX (transcription export) factors; SRC1 produces 2 splice variant proteins with different functions; alternative splicing of SRC1 pre-mRNA is promoted by Hub1p; mutant has aneuploidy tolerance; SEC1 has a paralog, HEH2, that arose from the whole genome duplication [Source:SGD;Acc:S000004497]
Gene Synonyms
HEH1, YML033W
Location
Chromosome XIII: 209,525-212,155 forward strand.
R64-1-1:BK006946.2
About this gene
This gene has 1 transcript (splice variant), 342 orthologues and 1 paralogue.
Transcripts
