Enzyme regulator; involved in synthesis of phosphatidylinositol 3,5-bisphosphate, in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; binds negative (Fig4p) and positive (Fab1p) regulators of PtdIns(3,5)P(2) to control endolysosome function; similar to mammalian Vac14p [Source:SGD;Acc:S000004378]
Chromosome XII: 893,628-896,270 forward strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant) and 217 orthologues.
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YLR386W_mRNA | VAC14 | 2643 | 880aa | YLR386W | Protein coding | Q06708 | Ensembl Canonical, |