Plasma membrane ATP-binding cassette (ABC) transporter; required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport; contains 12 transmembrane domains and two ATP binding domains; expressed only in MATa cells; human homolog ABCB1 mediates multidrug resistance in many chemotherapy-resistant tumors by effluxing toxic compounds from the cell [Source:SGD;Acc:S000001692]
Chromosome XI: 42,423-46,295 reverse strand.
R64-1-1:BK006944.2
This gene has 1 transcript (splice variant).
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YKL209C_mRNA | STE6 | 3873 | 1290aa | YKL209C | Protein coding | P12866 | Ensembl Canonical, |