Description
ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and Ubr1p; mutant has aneuploidy tolerance [Source:SGD;Acc:S000001628]
Gene Synonyms
CIM5, YTA3
Location
Chromosome XI: 174,213-175,616 forward strand.
R64-1-1:BK006944.2
About this gene
This gene has 1 transcript (splice variant), 234 orthologues and 5 paralogues.
Transcripts
