Description
Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins [Source:SGD;Acc:S000003922]
Location
Chromosome X: 742,848-743,999 reverse strand.
R64-1-1:BK006943.2
About this gene
This gene has 1 transcript (splice variant) and 13 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
|---|---|---|---|---|---|---|---|
| YJR161C_mRNA | COS5 | 1152 | 383aa | YJR161C | Protein coding | P47187 | Ensembl Canonical, |
