Description
Translation initiation factor eIF4A; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G; protein abundance increases in response to DNA replication stress; TIF2 has a paralog, TIF1, that arose from the whole genome duplication [Source:SGD;Acc:S000003674]
Gene Synonyms
eIF4A
Location
Chromosome X: 153,504-154,691 reverse strand.
R64-1-1:BK006943.2
About this gene
This gene has 1 transcript (splice variant), 229 orthologues and 22 paralogues.
Transcripts
