Component of the spindle-assembly checkpoint complex; delays onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p; regulates APC/C activity during prometaphase and metaphase of meiosis I; gene dosage imbalance between MAD1 and MAD2 leads to chromosome instability [Source:SGD;Acc:S000003567]
Chromosome X: 387,657-388,247 forward strand.
R64-1-1:BK006943.2
This gene has 1 transcript (splice variant) and 455 orthologues.
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YJL030W_mRNA | MAD2 | 591 | 196aa | YJL030W | Protein coding | P40958 | Ensembl Canonical, |