Subunit of spindle-assembly checkpoint complex; involved in delaying anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover; MAD3 has a paralog, BUB1, that arose from the whole genome duplication [Source:SGD;Acc:S000003550]
Chromosome X: 409,493-411,040 reverse strand.
R64-1-1:BK006943.2
This gene has 1 transcript (splice variant), 444 orthologues and 1 paralogue.
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YJL013C_mRNA | MAD3 | 1548 | 515aa | YJL013C | Protein coding | P47074 | Ensembl Canonical, |