Nuclear envelope/ER integral membrane protein; interacts and functions with Brr6p and Brl1p in lipid homeostasis; mutants are defective in nuclear pore complex biogenesis, nuclear envelope morphology, mRNA export from the nucleus and are sensitive to sterol biosynthesis inhibitors and membrane fluidizing agents; exhibits synthetic lethal genetic interactions with genes involved in lipid metabolism [Source:SGD;Acc:S000001302]
Chromosome IX: 277,723-278,139 forward strand.
R64-1-1:BK006942.2
This gene has 1 transcript (splice variant).
Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
---|---|---|---|---|---|---|---|
YIL040W_mRNA | APQ12 | 417 | 138aa | YIL040W | Protein coding | P40532 | Ensembl Canonical, |