Member of conserved ER transmembrane complex; required for efficient folding of proteins in the ER; null mutant displays induction of the unfolded protein response; homologous to worm ZK616.6/EMC-4 and fly CG11137; mutation is functionally complemented by human EMC4 [Source:SGD;Acc:S000003200]
Chromosome VII: 63,048-63,620 reverse strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant) and 202 orthologues.