Description
Evolutionarily-conserved 5'-3' exonuclease; component of cytoplasmic processing (P) bodies involved in mRNA decay; also enters the nucleus and positively regulates transcription initiation and elongation; plays a role in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, and telomere maintenance; activated by the scavenger decapping enzyme Dcs1p [Source:SGD;Acc:S000003141]
Gene Synonyms
DST2, KEM1, RAR5, SEP1, SKI1, XRN1
Location
Chromosome VII: 175,527-180,113 reverse strand.
R64-1-1:BK006941.2
About this gene
This gene has 1 transcript (splice variant), 220 orthologues and 1 paralogue.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
|---|---|---|---|---|---|---|---|
| YGL173C_mRNA | XRN1 | 4587 | 1528aa | YGL173C | Protein coding | P22147 | Ensembl Canonical, |
