Description
Mitochondrial protein kinase; negatively regulates activity of the pyruvate dehydrogenase complex by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp1p and phosphatases Ptc5p and Ptc6p; relocalizes from mitochondrion to cytoplasm upon DNA replication stress [Source:SGD;Acc:S000003027]
Location
Chromosome VII: 392,223-393,698 forward strand.
R64-1-1:BK006941.2
About this gene
This gene has 1 transcript (splice variant), 862 orthologues and 1 paralogue.
Transcripts
