Description
Activator of anaphase-promoting complex/cyclosome (APC/C); antagonist of the spindle assembly checkpoint; directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including: Cdc20p, Ase1p, Cin8p, Fin1p and Clb5p; partially active in metaphase, and fully active in anaphase; cell-cycle regulated [Source:SGD;Acc:S000002971]
Gene Synonyms
HCT1
Location
Chromosome VII: 492,474-494,174 reverse strand.
R64-1-1:BK006941.2
About this gene
This gene has 1 transcript (splice variant) and 2 paralogues.
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
|---|---|---|---|---|---|---|---|
| YGL003C_mRNA | CDH1 | 1701 | 566aa | YGL003C | Protein coding | P53197 | Ensembl Canonical, |
