Description
JmjC domain-containing histone demethylase; targets tri- and dimethylated H3K36; associates with actively transcribed regions and promotes elongation; repressor of autophagy-related genes in nutrient-replete conditions; damage-responsive repressor of PHR1; phosphorylated by the Rad53p-dependent DNA damage checkpoint pathway and by a Rim1p-mediated event during starvation; target of stress-induced hormesis; RPH1 has a paralog, GIS1, that arose from the whole genome duplication [Source:SGD;Acc:S000000971]
Gene Synonyms
KDM4
Location
Chromosome V: 523,369-525,759 forward strand.
R64-1-1:BK006939.2
About this gene
This gene has 1 transcript (splice variant).
Transcripts
| Transcript ID | Name | bp | Protein | Translation ID | Biotype | UniProt Match | Flags |
|---|---|---|---|---|---|---|---|
| YER169W_mRNA | RPH1 | 2391 | 796aa | YER169W | Protein coding | P39956 | Ensembl Canonical, |
