Description
Cytoplasmic glutaredoxin; thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress; GRX2 has two in-frame start codons resulting in a shorter isoform that is retained in the cytosol and a longer form translocated to the mitochondrial matrix; GRX2 has a paralog, GRX1, that arose from the whole genome duplication [Source:SGD;Acc:S000002921]
Gene Synonyms
TTR1
Location
Chromosome IV: 1,471,017-1,471,448 forward strand.
R64-1-1:BK006938.2
About this gene
This gene has 1 transcript (splice variant), 188 orthologues and 3 paralogues.
Transcripts
