Description
NADPH-dependent aldo-keto reductase; reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases; protein abundance increases in response to DNA replication stress; YPR1 has a paralog, GCY1, that arose from the whole genome duplication; human homolog AKR1B1 can complement yeast null mutant [Source:SGD;Acc:S000002776]
Location
Chromosome IV: 1,213,904-1,214,842 forward strand.
R64-1-1:BK006938.2
About this gene
This gene has 1 transcript (splice variant), 3061 orthologues and 9 paralogues.
Transcripts
