Description
Vacuolar glutathione S-conjugate transporter; ABC-C transporter of the ATP-binding cassette family; required for vacuole fusion; forms stable complexes with vacuole fusion machinery; regulates Vam7p recruitment to vacuoles; role in detoxifying metals (Cd, Hg, As); transports GSSG that is not immediately reduced in cytosol to vacuole; transports unconjugated bilirubin, selenodigluthatione, oxidized glutathione; similar to human cystic fibrosis protein CFTR [Source:SGD;Acc:S000002542]
Location
Chromosome IV: 723,004-727,551 reverse strand.
R64-1-1:BK006938.2
About this gene
This gene has 1 transcript (splice variant), 594 orthologues and 5 paralogues.
Transcripts
